1h9y
From Proteopedia
(New page: 200px<br /> <applet load="1h9y" size="450" color="white" frame="true" align="right" spinBox="true" caption="1h9y, resolution 2.4Å" /> '''CYTOCHROME CD1 NITRI...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1H9Y is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Paracoccus_pantotrophus Paracoccus pantotrophus]] with SO4, CYN, HEC and DHE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1H9Y OCA]]. | + | 1H9Y is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Paracoccus_pantotrophus Paracoccus pantotrophus]] with SO4, CYN, HEC and DHE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Sites: C1A, C1B, D1A and D1B. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1H9Y OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:20:46 2007'' |
Revision as of 12:16, 30 October 2007
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CYTOCHROME CD1 NITRITE REDUCTASE, REDUCED FORM COMPLEXED TO CN
Overview
Cytochrome cd(1) nitrite reductase is a bifunctional enzyme, which can, catalyze the 1-electron reduction of nitrite to nitric oxide and the, 4-electron reduction of dioxygen to water. Here we describe the structure, of reduced nitrite reductase, crystallized under anaerobic conditions. The, structure reveals substantial domain rearrangements with the c domain, rotated by 60 degrees and shifted by approximately 20 A compared with, previously known structures from crystals grown under oxidizing, conditions. This alternative conformation gives rise to different electron, transfer routes between the c and d(1) domains and points to the, involvement of elements of very large structural changes in the function, in this enzyme. In the present structure, the c heme has a His-69/Met-106, ... [(full description)]
About this Structure
1H9Y is a [Single protein] structure of sequence from [Paracoccus pantotrophus] with SO4, CYN, HEC and DHE as [ligands]. Structure known Active Sites: C1A, C1B, D1A and D1B. Full crystallographic information is available from [OCA].
Reference
The Structure of an alternative form of Paracoccus pantotrophus cytochrome cd(1) nitrite reductase., Sjogren T, Hajdu J, J Biol Chem. 2001 Aug 3;276(31):29450-5. Epub 2001 May 23. PMID:11373294
Page seeded by OCA on Tue Oct 30 14:20:46 2007
Categories: Paracoccus pantotrophus | Single protein | Hajdu, J. | Sjogren, T. | CYN | DHE | HEC | SO4 | Cn | Enzyme | Nitrite reductase | Oxidoreductase
