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(→Outer Surface Protein A (OspA)) |
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<Structure load='1fj1' size='500' frame='true' align='right' caption='Outer Surface Protein A Fab LA-2 Complex' scene='Insert optional scene name here' /> | <Structure load='1fj1' size='500' frame='true' align='right' caption='Outer Surface Protein A Fab LA-2 Complex' scene='Insert optional scene name here' /> | ||
| - | Outer surface protein A (OspA) is a major lipoprotein on the borrelia burgdorferi spirochete which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions such as late stage neurological disorders that are associated with Lyme Disease. | + | Outer surface protein A (OspA) is a major lipoprotein[http://en.wikipedia.org/wiki/Lipoprotein]on the borrelia burgdorferi spirochete which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions such as late stage neurological disorders that are associated with Lyme Disease. |
== Introduction to Lyme Disease == | == Introduction to Lyme Disease == | ||
== Structure == | == Structure == | ||
Revision as of 03:32, 16 August 2012
Outer Surface Protein A (OspA)
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Outer surface protein A (OspA) is a major lipoprotein[1]on the borrelia burgdorferi spirochete which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions such as late stage neurological disorders that are associated with Lyme Disease.
