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4a55
From Proteopedia
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{{STRUCTURE_4a55| PDB=4a55 | SCENE= }} | {{STRUCTURE_4a55| PDB=4a55 | SCENE= }} | ||
===Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108=== | ===Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108=== | ||
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{{ABSTRACT_PUBMED_22120714}} | {{ABSTRACT_PUBMED_22120714}} | ||
==About this Structure== | ==About this Structure== | ||
[[4a55]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A55 OCA]. | [[4a55]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A55 OCA]. | ||
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| + | ==See Also== | ||
| + | *[[Phsphatidylinositol 3-kinase|Phsphatidylinositol 3-kinase]] | ||
==Reference== | ==Reference== | ||
Revision as of 05:36, 29 August 2012
Contents |
Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108
Template:ABSTRACT PUBMED 22120714
About this Structure
4a55 is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Hon WC, Berndt A, Williams RL. Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases. Oncogene. 2011 Nov 28. doi: 10.1038/onc.2011.532. PMID:22120714 doi:10.1038/onc.2011.532
Categories: Homo sapiens | Mus musculus | Berndt, A. | Hon, W C. | Williams, R L. | Cancer mutation | Enzyme regulation | Growth factor signalling | Lipid kinase | Membrane binding | Non-atp competitive ligand binding site | Oncogene | Pi3-kinase inhibitor | Structure-activity relationship | Transferase | Tumour
