Argonaute
From Proteopedia
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| - | The Argonaute family of proteins is central to the RNA-induced silencing in eukaryotic organisms <ref>pmid 22539551</ref>. It was first found to be important for plant development and for germline stem-cell division in ''Drosophila Melanogaster'', but further research revealed a much broader and essential role in protein synthesis, maintenance of genome integrity and RNA stability <ref>pmid 18073770</ref>. | ||
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<StructureSection load='4EI1' size='350' side='right' caption='Structure of human Argonaute2 protein in complex with target RNA (PDB Entry [[4EI1]])' scene=''> | <StructureSection load='4EI1' size='350' side='right' caption='Structure of human Argonaute2 protein in complex with target RNA (PDB Entry [[4EI1]])' scene=''> | ||
| + | The Argonaute family of proteins is central to the RNA-induced silencing in eukaryotic organisms <ref>pmid 22539551</ref>. It was first found to be important for plant development and for germline stem-cell division in ''Drosophila Melanogaster'', but further research revealed a much broader and essential role in protein synthesis, maintenance of genome integrity and RNA stability <ref>pmid 18073770</ref>. | ||
</StructureSection> | </StructureSection> | ||
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==The Argonaute Family== | ==The Argonaute Family== | ||
===Role in RNA interference=== | ===Role in RNA interference=== | ||
Revision as of 08:43, 6 September 2012
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Contents |
The Argonaute Family
Role in RNA interference
Members
Structure
N Domain
Paz Domain
Mid Domain
Piwi Domain
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, João Rodrigues, Joel L. Sussman, Alexander Berchansky
