User:Josie N. Harmon/Sandbox 1
From Proteopedia
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Xanthine oxidase is characterized as a molybdenum containing enzyme that catalyzes the hydroxylation of a sp2 hybrized carbon in a broad range of aromatic heterocycles and aldehydes. | Xanthine oxidase is characterized as a molybdenum containing enzyme that catalyzes the hydroxylation of a sp2 hybrized carbon in a broad range of aromatic heterocycles and aldehydes. | ||
| - | The 6-mercaptopurine complex consists of | + | The 6-mercaptopurine complex consists of a total of <scene name='User:Josie_N._Harmon/Sandbox_1/Mercap_ligands/1'>five different ligands</scene> encased within the xanthine oxidase protein complex. These ligands include: Flavin-Adenine Dinucleotide, Fe2S2 clusters, Dioxothiomolybdenum (VI) ion, Phosphonic acidmono-(2-amino-5,6-dimercapto- 4-oxo-3,7,8A,9,10,10A-hexahydro-4H-8-oxo- 1,3,9,10-tetraaza-anthracen-7-ylmethyl)ester, and 9H-purine-6-thiol. |
| - | A <scene name='User:Josie_N._Harmon/Sandbox_1/6mercaptopurine_ligand/3'>secondary depiction</scene> of the structure is represented with purple arrows representing the alpha helix structures and gold arrows representing the beta strand structures. | + | A <scene name='User:Josie_N._Harmon/Sandbox_1/6mercaptopurine_ligand/3'>secondary depiction</scene> of the structure is represented with purple arrows representing the alpha helix structures and gold arrows representing the beta strand structures. The <scene name='User:Josie_N._Harmon/Sandbox_1/Mercap_helix_blue/1'>helices </scene>of the protein backbone can also be noted by the blue arrows on the structure. |
Revision as of 17:42, 19 September 2012
Xanthine Oxidase in Complex with 6-Mercaptopurine
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Xanthine oxidase is characterized as a molybdenum containing enzyme that catalyzes the hydroxylation of a sp2 hybrized carbon in a broad range of aromatic heterocycles and aldehydes.
The 6-mercaptopurine complex consists of a total of encased within the xanthine oxidase protein complex. These ligands include: Flavin-Adenine Dinucleotide, Fe2S2 clusters, Dioxothiomolybdenum (VI) ion, Phosphonic acidmono-(2-amino-5,6-dimercapto- 4-oxo-3,7,8A,9,10,10A-hexahydro-4H-8-oxo- 1,3,9,10-tetraaza-anthracen-7-ylmethyl)ester, and 9H-purine-6-thiol.
A of the structure is represented with purple arrows representing the alpha helix structures and gold arrows representing the beta strand structures. The of the protein backbone can also be noted by the blue arrows on the structure.
