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1k4h
From Proteopedia
(New page: 200px<br /><applet load="1k4h" size="450" color="white" frame="true" align="right" spinBox="true" caption="1k4h, resolution 1.80Å" /> '''CRYSTAL STRUCTURE OF...) |
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| - | [[Image:1k4h.jpg|left|200px]]<br /><applet load="1k4h" size=" | + | [[Image:1k4h.jpg|left|200px]]<br /><applet load="1k4h" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1k4h, resolution 1.80Å" /> | caption="1k4h, resolution 1.80Å" /> | ||
'''CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one'''<br /> | '''CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 1K4H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis] with ZN and APQ as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] Full crystallographic information is available from [http:// | + | 1K4H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=APQ:'>APQ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Queuine_tRNA-ribosyltransferase Queuine tRNA-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.29 2.4.2.29] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K4H OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Zymomonas mobilis]] | [[Category: Zymomonas mobilis]] | ||
[[Category: Brenk, R.]] | [[Category: Brenk, R.]] | ||
| - | [[Category: Castellano, R | + | [[Category: Castellano, R K.]] |
[[Category: Diederich, F.]] | [[Category: Diederich, F.]] | ||
[[Category: Furler, M.]] | [[Category: Furler, M.]] | ||
[[Category: Klebe, G.]] | [[Category: Klebe, G.]] | ||
| - | [[Category: Meyer, E | + | [[Category: Meyer, E A.]] |
| - | [[Category: Stubbs, M | + | [[Category: Stubbs, M T.]] |
[[Category: APQ]] | [[Category: APQ]] | ||
[[Category: ZN]] | [[Category: ZN]] | ||
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[[Category: trna-modifying enzyme]] | [[Category: trna-modifying enzyme]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:30:07 2008'' |
Revision as of 11:30, 21 February 2008
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CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one
About this Structure
1K4H is a Single protein structure of sequence from Zymomonas mobilis with and as ligands. Active as Queuine tRNA-ribosyltransferase, with EC number 2.4.2.29 Full crystallographic information is available from OCA.
Reference
De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity., Meyer EA, Brenk R, Castellano RK, Furler M, Klebe G, Diederich F, Chembiochem. 2002 Mar 1;3(2-3):250-3. PMID:11921407
Page seeded by OCA on Thu Feb 21 13:30:07 2008
