3n7y
From Proteopedia
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{{STRUCTURE_3n7y| PDB=3n7y | SCENE= }} | {{STRUCTURE_3n7y| PDB=3n7y | SCENE= }} | ||
===Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV=== | ===Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV=== | ||
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{{ABSTRACT_PUBMED_21116482}} | {{ABSTRACT_PUBMED_21116482}} | ||
==About this Structure== | ==About this Structure== | ||
[[3n7y]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7Y OCA]. | [[3n7y]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7Y OCA]. | ||
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| + | ==See Also== | ||
| + | *[[Growth factor receptor-bound protein 2|Growth factor receptor-bound protein 2]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021116482</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Clements, J H.]] | [[Category: Clements, J H.]] | ||
[[Category: Martin, S F.]] | [[Category: Martin, S F.]] | ||
[[Category: Whiddon, B B.]] | [[Category: Whiddon, B B.]] | ||
| + | [[Category: Golgi apparatus]] | ||
| + | [[Category: Host-virus interaction]] | ||
| + | [[Category: Ligand preorganization]] | ||
| + | [[Category: Macrocycle]] | ||
| + | [[Category: Macrocyclic ligand]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Protein binding-peptide complex]] | ||
Revision as of 14:14, 20 October 2012
Contents |
Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV
Template:ABSTRACT PUBMED 21116482
About this Structure
3n7y is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Delorbe JE, Clements JH, Whiddon BB, Martin SF. Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions. ACS Med Chem Lett. 2010 Nov 11;1(8):448-452. PMID:21116482 doi:10.1021/ml100142y
