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2pfh

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==About this Structure==
==About this Structure==
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[[2pfh]] is a 1 chain structure of [[Aldose Reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFH OCA].
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[[2pfh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFH OCA].
==See Also==
==See Also==

Revision as of 17:51, 20 October 2012

Image:2pfh.png

Template:STRUCTURE 2pfh

Contents

Complex of Aldose Reductase with NADP+ and simaltaneously bound competetive inhibitors Fidarestat and IDD594. Concentration of Fidarestat in soaking solution is less than concentration of IDD594.

Template:ABSTRACT PUBMED 22752989

About this Structure

2pfh is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Cousido-Siah A, Petrova T, Hazemann I, Mitschler A, Ruiz FX, Howard E, Ginell S, Atmanene C, Van Dorsselaer A, Sanglier-Cianferani S, Joachimiak A, Podjarny A. Crystal packing modifies ligand binding affinity: The case of aldose reductase. Proteins. 2012 Jul 2. doi: 10.1002/prot.24136. PMID:22752989 doi:10.1002/prot.24136

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