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2x0u

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==About this Structure==
==About this Structure==
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[[2x0u]] is a 2 chain structure of [[P53]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0U OCA].
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[[2x0u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X0U OCA].
==See Also==
==See Also==

Revision as of 19:12, 20 October 2012

Image:2x0u.png

Template:STRUCTURE 2x0u

Contents

STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-AMINO SUBSTITUTED BENZOTHIAZOLE SCAFFOLD

Template:ABSTRACT PUBMED 20142040

About this Structure

2x0u is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Basse N, Kaar JL, Settanni G, Joerger AC, Rutherford TJ, Fersht AR. Toward the rational design of p53-stabilizing drugs: probing the surface of the oncogenic Y220C mutant. Chem Biol. 2010 Jan 29;17(1):46-56. PMID:20142040 doi:10.1016/j.chembiol.2009.12.011
  • Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

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