2b0i

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Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution.
Image:2b0i.png

Template:STRUCTURE 2b0i

COMPUTER MODEL OF A COVALENT COMPLEX BETWEEN D(GTATGGCCATAC) AND TWO MOLECULES OF ANTITUMOR DRUG TRABECTEDIN.

Template:ABSTRACT PUBMED 16150929

Reference

  • Marco E, Gago F. DNA structural similarity in the 2:1 complexes of the antitumor drugs trabectedin (Yondelis) and chromomycin A3 with an oligonucleotide sequence containing two adjacent TGG binding sites on opposing strands. Mol Pharmacol. 2005 Dec;68(6):1559-67. Epub 2005 Sep 8. PMID:16150929 doi:10.1124/mol.105.015685

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