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Template:STRUCTURE 1d5r

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(New page: {{Structure |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1d5r, resolution 2.1&Aring; (<scene name='initialview01'>initial scene</scene>) |SITE= |LIGAND= <scene name='pdbligand=TLA:...)
Current revision (20:20, 21 October 2012) (edit) (undo)
 
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{{Structure
{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1d5r, resolution 2.1&Aring; (<scene name='initialview01'>initial scene</scene>)
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1d5r]], [[Resolution|resolution]] 2.10&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|SITE=
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|LIGAND= <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>
|LIGAND= <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span>
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|GENE=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d5r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d5r RCSB], [http://www.ebi.ac.uk/pdbsum/1d5r PDBsum]</span>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG2453 CDC14]</span>
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|FUNCTION={{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0016791 | text = phosphoric monoester hydrolase activity}}{{GO|id=GO:0008289 | text = lipid binding}}{{GO|id=GO:0051717 | text = inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity}}{{GO|id=GO:0030165 | text = PDZ domain binding}}{{GO|id=GO:0008138 | text = protein tyrosine/serine/threonine phosphatase activity}}{{GO|id=GO:0004721 | text = phosphoprotein phosphatase activity}}{{GO|id=GO:0051800 | text = phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0016314 | text = phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity}}{{GO|id=GO:0004725 | text = protein tyrosine phosphatase activity}}{{GO|id=GO:0004722 | text = protein serine/threonine phosphatase activity}}{{GO|id=GO:0004438 | text = phosphatidylinositol-3-phosphatase activity}}
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|RELATEDENTRY=
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|PROCESS={{GO|id=GO:0046856 | text = phosphoinositide dephosphorylation}}{{GO|id=GO:0006917 | text = induction of apoptosis}}{{GO|id=GO:0048738 | text = cardiac muscle development}}{{GO|id=GO:0016477 | text = cell migration}}{{GO|id=GO:0007507 | text = heart development}}{{GO|id=GO:0001525 | text = angiogenesis}}{{GO|id=GO:0045786 | text = negative regulation of cell cycle}}{{GO|id=GO:0031647 | text = regulation of protein stability}}{{GO|id=GO:0016311 | text = dephosphorylation}}{{GO|id=GO:0046855 | text = inositol phosphate dephosphorylation}}{{GO|id=GO:0043066 | text = negative regulation of apoptosis}}{{GO|id=GO:0007049 | text = cell cycle}}{{GO|id=GO:0051898 | text = negative regulation of protein kinase B signaling cascade}}{{GO|id=GO:0007417 | text = central nervous system development}}{{GO|id=GO:0006629 | text = lipid metabolic process}}{{GO|id=GO:0051895 | text = negative regulation of focal adhesion formation}}{{GO|id=GO:0043542 | text = endothelial cell migration}}{{GO|id=GO:0000079 | text = regulation of cyclin-dependent protein kinase activity}}{{GO|id=GO:0008283 | text = cell proliferation}}{{GO|id=GO:0030336 | text = negative regulation of cell migration}}{{GO|id=GO:0006470 | text = protein amino acid dephosphorylation}}{{GO|id=GO:0008285 | text = negative regulation of cell proliferation}}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d5r OCA], [http://www.ebi.ac.uk/pdbsum/1d5r PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1d5r RCSB]</span>
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|COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}
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|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1d5rA02 1D5Ra02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1d5rA01 1D5Ra01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014020 Ipr014020], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000340 Ipr000340], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000387 Ipr000387], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008973 Ipr008973], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000242 Ipr000242], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014019 Ipr014019]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00782 PF00782]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=23181 d1d5ra1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=32697 d1d5ra2]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P60484 P60484]</span>
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|uPDB=1D5R|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
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{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
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{{!}} '''Toggle Conservation Colors:'''
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{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
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Rows = identical sequences:
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<jmol>
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<jmolButton>
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<script></script>
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<text>A [x]</text>
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<name>jmb_1d5r_A</name>
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<title>toggle chain A</title>
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<jsscript>ConsurfChainButton(elementClicked)</jsscript>
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<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
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</jmolButton>
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</jmol>
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}}
}}

Current revision

Drag the structure with the mouse to rotate
1d5r, resolution 2.10Å ()
Ligands:
Activity: Protein-tyrosine-phosphatase, with EC number 3.1.3.48
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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