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Template:STRUCTURE 1bzy

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Current revision

1bzy, resolution 2.00Å ()

Ligands:

, ,

Activity:

Hypoxanthine phosphoribosyltransferase, with EC number 2.4.2.8

Structural annotation:
Resources:	CATH : 1Bzya00, 1Bzyb00, 1Bzyc00, 1Bzyd00 InterPro : Ipr005904, Ipr002375, Ipr000836 Pfam : PF00156 SCOP : d1bzya_, d1bzyb_, d1bzyc_, d1bzyd_ UniProt : P00492

Functional annotation:
Cellular component:	cytoplasm
Biological process:	purine nucleotide biosynthetic process purine ribonucleoside salvage nucleoside metabolic process hypoxanthine metabolic process protein homotetramerization behavior positive regulation of dopamine metabolic process
Molecular function:	transferase activity, transferring glycosyl groups hypoxanthine phosphoribosyltransferase activity protein binding protein homodimerization activity transferase activity magnesium ion binding metal ion binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1bzy"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1bzy, resolution 2.00&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1bzy]], [[Resolution|resolution]] 2.00&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |LIGAND= <scene name='pdbligand=IMU:PHOSPHORIC+ACID+MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL]+ESTER'>IMU</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0634 Hpt]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bzy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bzy RCSB], [http://www.ebi.ac.uk/pdbsum/1bzy PDBsum]</span>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bzy OCA], [http://www.ebi.ac.uk/pdbsum/1bzy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1bzy RCSB]</span>
 |FUNCTION={{GO|id=GO:0016757 | text = transferase activity, transferring glycosyl groups}}{{GO|id=GO:0004422 | text = hypoxanthine phosphoribosyltransferase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0042803 | text = protein homodimerization activity}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0046872 | text = metal ion binding}}
 |PROCESS={{GO|id=GO:0006164 | text = purine nucleotide biosynthetic process}}{{GO|id=GO:0006166 | text = purine ribonucleoside salvage}}{{GO|id=GO:0009116 | text = nucleoside metabolic process}}{{GO|id=GO:0046100 | text = hypoxanthine metabolic process}}{{GO|id=GO:0051289 | text = protein homotetramerization}}{{GO|id=GO:0007610 | text = behavior}}{{GO|id=GO:0045964 | text = positive regulation of dopamine metabolic process}}
 |COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyA00 1Bzya00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyB00 1Bzyb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyC00 1Bzyc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1bzyD00 1Bzyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR005904 Ipr005904], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002375 Ipr002375], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000836 Ipr000836]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00156 PF00156]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34071 d1bzya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34072 d1bzyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34073 d1bzyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=34074 d1bzyd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P00492 P00492]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P00492 P00492]</span>
+|uPDB=1BZY|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_1bzy_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_1bzy_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>C [x]</text>
+<name>jmb_1bzy_C</name>
+<title>toggle chain C</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>D [x]</text>
+<name>jmb_1bzy_D</name>
+<title>toggle chain D</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 1bzy

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