Interferon regulatory factor

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'''Interferon regulatory factor''' (IRF) regulate transcription of interferons. IRF-1 functions as a transcriptional activator by binding to an interferon-stimulated response element in the gene promoter. IRF-3 and IRF-7 are activated by viruses or after binding to Toll-like receptors. IRF-4 is lymphoid-specific and functions in the development of immune cells.
'''Interferon regulatory factor''' (IRF) regulate transcription of interferons. IRF-1 functions as a transcriptional activator by binding to an interferon-stimulated response element in the gene promoter. IRF-3 and IRF-7 are activated by viruses or after binding to Toll-like receptors. IRF-4 is lymphoid-specific and functions in the development of immune cells.

Revision as of 10:12, 5 November 2012

Structure of mouse interferon regulatory factor DNA-binding domain dimer complex with DNA (PDB entry 1if1)

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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