Methanol dehydrogenase
From Proteopedia
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| - | {{STRUCTURE_2ad6| PDB=2ad6 | SIZE=400| SCENE= |right| CAPTION=Methanol dehydrogenase complex with cofactor PQQ and Ca+2 ion, [[2ad6]] }} | + | {{STRUCTURE_2ad6| PDB=2ad6 | SIZE=400| SCENE= |right| CAPTION=Methanol dehydrogenase large subunit (grey and pink) and small subunit (green and yellow) complex with cofactor PQQ and Ca+2 ion, [[2ad6]] }} |
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Revision as of 10:06, 6 November 2012
Methanol dehydrogenase (MDH) is a quinoprotein which catalyzes the conversion of methanol and NAD+ or NADP+ to formaldeyde and NADH or NADPH and H+. MDH is a pyrroloquinoline quinone (PQQ) -dependent enzyme. MDH requires a divalent cation like Ca+2 for catalytic activity.
3D structures of methanol dehydrogenase
4aah, 1g72, 2ad6, 2ad7, 2ad8 – MmMDH α+β + Ca + PQQ – Methylophilus methylotrophus
1h4i, 1w6s - MeMDH α+β + Ca + PQQ – Methylobacterium extorquens
1h4j - MeMDH α (mutant) +β + Ca + PQQ
1lrw - MDH α+β + Ca + PQQ – Paracoccus denitrificans
2d0v - MDH α+β + Ca + PQQ – Hyphomicrobium denitrificans
