Severin

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{{STRUCTURE_1svy| PDB=1svy | SCENE= |CAPTION=Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]] }}
{{STRUCTURE_1svy| PDB=1svy | SCENE= |CAPTION=Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]] }}
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[[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, ''i.e.'' the human severin ([[3fg6]]). It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well. The image at the right is the severin with <scene name='Severin/Cv/5'>calcium ions</scene> (<font color='lime'><b>colored lime</b></font>).
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[[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, ''i.e.'' the human severin ([[3fg6]]). It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well.
== 3D Structures of Severin ==
== 3D Structures of Severin ==

Revision as of 09:59, 15 November 2012

Crystal Structure of Human Severin, 3fg6
Crystal Structure of Human Severin, 3fg6

Template:STRUCTURE 1svy

Severin is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, i.e. the human severin (3fg6). It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well.

3D Structures of Severin

3fg6 – Adseverin C-terminal – human
1svy – DdSeverin domain 2 – Dictyostelium discoideum
1svq, 1svr - DdSeverin domain 2 - Dictyostelium discoideum, NMR

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Jaime Prilusky

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