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Template:STRUCTURE 1j1c
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{{Structure | {{Structure | ||
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1j1c, resolution 2. | + | |PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1j1c]], [[Resolution|resolution]] 2.10Å (<scene name='initialview01'>default scene</scene>)}}} |
| - | + | |LIGAND= <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> | |
| - | |LIGAND= <scene name='pdbligand=ADP:ADENOSINE-5 | + | |
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span> | ||
| - | |GENE= | ||
| - | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00220 S_TKc]</span> | ||
|RELATEDENTRY=[[1j1b|1j1b]] | |RELATEDENTRY=[[1j1b|1j1b]] | ||
| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1c OCA], [http://www.ebi.ac.uk/pdbsum/1j1c PDBsum], [http://www. | + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1j1c RCSB], [http://www.ebi.ac.uk/pdbsum/1j1c PDBsum]</span> |
| + | |FUNCTION={{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0005524 | text = ATP binding}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0004674 | text = protein serine/threonine kinase activity}}{{GO|id=GO:0051059 | text = NF-kappaB binding}}{{GO|id=GO:0004696 | text = glycogen synthase kinase 3 activity}}{{GO|id=GO:0004672 | text = protein kinase activity}}{{GO|id=GO:0002039 | text = p53 binding}} | ||
| + | |PROCESS={{GO|id=GO:0006983 | text = ER overload response}}{{GO|id=GO:0046827 | text = positive regulation of protein export from nucleus}}{{GO|id=GO:0018105 | text = peptidyl-serine phosphorylation}}{{GO|id=GO:0005977 | text = glycogen metabolic process}}{{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0060070 | text = Wnt receptor signaling pathway through beta-catenin}}{{GO|id=GO:0007242 | text = intracellular signaling cascade}}{{GO|id=GO:0043066 | text = negative regulation of apoptosis}}{{GO|id=GO:0016055 | text = Wnt receptor signaling pathway}} | ||
| + | |COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}{{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0030877 | text = beta-catenin destruction complex}} | ||
| + | |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1j1cA02 1J1Ca02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1j1cA01 1J1Ca01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1j1cB02 1J1Cb02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1j1cB01 1J1Cb01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011009 Ipr011009], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002290 Ipr002290], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008271 Ipr008271], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000719 Ipr000719]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00069 PF00069]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=90760 d1j1ca_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=90761 d1j1cb_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P49841 P49841]</span> | ||
| + | |uPDB=1J1C|CONSURF={{!}}- | ||
| + | {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]] | ||
| + | {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" | ||
| + | {{!}} '''Toggle Conservation Colors:''' | ||
| + | {{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}} | ||
| + | Rows = identical sequences: | ||
| + | <jmol> | ||
| + | <jmolButton> | ||
| + | <script></script> | ||
| + | <text>A [x]</text> | ||
| + | <name>jmb_1j1c_A</name> | ||
| + | <title>toggle chain A</title> | ||
| + | <jsscript>ConsurfChainButton(elementClicked)</jsscript> | ||
| + | <appendtargetsuffixtoid>true</appendtargetsuffixtoid> | ||
| + | </jmolButton> | ||
| + | </jmol> | ||
| + | <jmol> | ||
| + | <jmolButton> | ||
| + | <script></script> | ||
| + | <text>B [x]</text> | ||
| + | <name>jmb_1j1c_B</name> | ||
| + | <title>toggle chain B</title> | ||
| + | <jsscript>ConsurfChainButton(elementClicked)</jsscript> | ||
| + | <appendtargetsuffixtoid>true</appendtargetsuffixtoid> | ||
| + | </jmolButton> | ||
| + | </jmol> | ||
| + | |||
}} | }} | ||
Current revision
