1e20

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Revision as of 12:59, 30 October 2007


1e20, resolution 2.02Å

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THE FMN BINDING PROTEIN ATHAL3

Overview

BACKGROUND: The Arabidopsis thaliana HAL3 gene product encodes for an, FMN-binding protein (AtHal3) that is related to plant growth and salt and, osmotic tolerance. AtHal3 shows sequence homology to ScHal3, a regulatory, subunit of the Saccharomyces cerevisae serine/threonine phosphatase PPz1., It has been proposed that AtHal3 and ScHal3 have similar roles in cellular, physiology, as Arabidopsis transgenic plants that overexpress AtHal3 and, yeast cells that overexpress ScHal3 display similar phenotypes of improved, salt tolerance. The enzymatic activity of AtHal3 has not been, investigated. However, the AtHal3 sequence is homologous to that of EpiD, a flavoprotein from Staphylococcus epidermidis that recognizes a peptidic, substrate and subsequently catalyzes the alpha, ... [(full description)]

About this Structure

1E20 is a [Single protein] structure of sequence from [Arabidopsis thaliana] with NI, FMN and BME as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

The X-ray structure of the FMN-binding protein AtHal3 provides the structural basis for the activity of a regulatory subunit involved in signal transduction., Albert A, Martinez-Ripoll M, Espinosa-Ruiz A, Yenush L, Culianez-Macia FA, Serrano R, Structure. 2000 Sep 15;8(9):961-9. PMID:10986463

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