1m4u
From Proteopedia
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[[Image:1m4u.png|left|200px]] | [[Image:1m4u.png|left|200px]] | ||
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{{STRUCTURE_1m4u| PDB=1m4u | SCENE= }} | {{STRUCTURE_1m4u| PDB=1m4u | SCENE= }} | ||
===Crystal structure of Bone Morphogenetic Protein-7 (BMP-7) in complex with the secreted antagonist Noggin=== | ===Crystal structure of Bone Morphogenetic Protein-7 (BMP-7) in complex with the secreted antagonist Noggin=== | ||
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{{ABSTRACT_PUBMED_12478285}} | {{ABSTRACT_PUBMED_12478285}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Stapes ankylosis syndrome without symphalangism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602991 602991]], Symphalangism, proximal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602991 602991]], Synostoses syndrome, multiple, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602991 602991]], Tarsal-carpal coalition syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602991 602991]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1m4u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M4U OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012478285</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Affolter, M.]] | [[Category: Affolter, M.]] | ||
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[[Category: Bone morphogenetic protein]] | [[Category: Bone morphogenetic protein]] | ||
[[Category: Cystine knot]] | [[Category: Cystine knot]] | ||
| - | [[Category: Hormone | + | [[Category: Hormone-growth factor complex]] |
[[Category: Noggin]] | [[Category: Noggin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 7 22:01:32 2010'' | ||
Revision as of 20:26, 5 December 2012
Crystal structure of Bone Morphogenetic Protein-7 (BMP-7) in complex with the secreted antagonist Noggin
Template:ABSTRACT PUBMED 12478285
About this Structure
1m4u is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Belmonte JC, Choe S. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature. 2002 Dec 12;420(6916):636-42. PMID:12478285 doi:10.1038/nature01245
