This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1p4r
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1p4r.png|left|200px]] | [[Image:1p4r.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1p4r", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1p4r| PDB=1p4r | SCENE= }} | {{STRUCTURE_1p4r| PDB=1p4r | SCENE= }} | ||
===Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD=== | ===Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_14966129}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 14966129 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_14966129}} | {{ABSTRACT_PUBMED_14966129}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1p4r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P4R OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014966129</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Beardsley, G P.]] | [[Category: Beardsley, G P.]] | ||
| Line 33: | Line 21: | ||
[[Category: Atic]] | [[Category: Atic]] | ||
[[Category: Bw1540u88ud]] | [[Category: Bw1540u88ud]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Purine biosynthesis]] | [[Category: Purine biosynthesis]] | ||
| - | + | [[Category: Transferase]] | |
| - | + | ||
Revision as of 11:47, 19 December 2012
Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD
Template:ABSTRACT PUBMED 14966129
About this Structure
1p4r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:14966129 doi:10.1074/jbc.M313691200
