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1rw8

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[[Image:1rw8.png|left|200px]]
[[Image:1rw8.png|left|200px]]
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{{STRUCTURE_1rw8| PDB=1rw8 | SCENE= }}
{{STRUCTURE_1rw8| PDB=1rw8 | SCENE= }}
===Crystal Structure of TGF-beta receptor I kinase with ATP site inhibitor===
===Crystal Structure of TGF-beta receptor I kinase with ATP site inhibitor===
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{{ABSTRACT_PUBMED_15177479}}
{{ABSTRACT_PUBMED_15177479}}
==About this Structure==
==About this Structure==
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1RW8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW8 OCA].
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[[1rw8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW8 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:15177479</ref><references group="xtra"/>
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<ref group="xtra">PMID:015177479</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Protein kinase]]
[[Category: Protein kinase]]
[[Category: Tgf-beta receptor i]]
[[Category: Tgf-beta receptor i]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:21:22 2009''
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Revision as of 10:07, 4 January 2013

Template:STRUCTURE 1rw8

Crystal Structure of TGF-beta receptor I kinase with ATP site inhibitor

Template:ABSTRACT PUBMED 15177479

About this Structure

1rw8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sawyer JS, Beight DW, Britt KS, Anderson BD, Campbell RM, Goodson T Jr, Herron DK, Li HY, McMillen WT, Mort N, Parsons S, Smith EC, Wagner JR, Yan L, Zhang F, Yingling JM. Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3581-4. PMID:15177479 doi:http://dx.doi.org/10.1016/j.bmcl.2004.04.007

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