1x7y
From Proteopedia
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[[Image:1x7y.png|left|200px]] | [[Image:1x7y.png|left|200px]] | ||
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{{STRUCTURE_1x7y| PDB=1x7y | SCENE= }} | {{STRUCTURE_1x7y| PDB=1x7y | SCENE= }} | ||
===Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase=== | ===Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase=== | ||
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{{ABSTRACT_PUBMED_15576032}} | {{ABSTRACT_PUBMED_15576032}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Maple syrup urine disease, type Ia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608348 608348]], Maple syrup urine disease, type Ib OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=248611 248611]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1x7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X7Y OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015576032</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chuang, D T.]] | [[Category: Chuang, D T.]] | ||
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[[Category: Branched-chain]] | [[Category: Branched-chain]] | ||
[[Category: Flavoprotein]] | [[Category: Flavoprotein]] | ||
+ | [[Category: Ketoacid dehydrogenase]] | ||
[[Category: Multi-enzyme complex]] | [[Category: Multi-enzyme complex]] | ||
[[Category: Oxidative decarboxylation maple syrup urine disease]] | [[Category: Oxidative decarboxylation maple syrup urine disease]] | ||
- | [[Category: Oxidoreductase | + | [[Category: Oxidoreductase]] |
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Thiamin diphosphate]] | [[Category: Thiamin diphosphate]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:54:15 2009'' |
Revision as of 11:50, 5 January 2013
Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase
Template:ABSTRACT PUBMED 15576032
About this Structure
1x7y is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wynn RM, Kato M, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation. Structure. 2004 Dec;12(12):2185-96. PMID:15576032 doi:10.1016/j.str.2004.09.013
Categories: Homo sapiens | Chuang, D T. | Chuang, J L. | Kato, M. | Li, J. | Machius, M. | Tomchick, D R. | Wynn, R M. | Acylation | Branched-chain | Flavoprotein | Ketoacid dehydrogenase | Multi-enzyme complex | Oxidative decarboxylation maple syrup urine disease | Oxidoreductase | Phosphorylation | Thiamin diphosphate