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2bmc

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Revision as of 09:56, 6 January 2013

Image:2bmc.png

Template:STRUCTURE 2bmc

AURORA-2 T287D T288D COMPLEXED WITH PHA-680632

Template:ABSTRACT PUBMED 15828847

About this Structure

2bmc is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Fancelli D, Berta D, Bindi S, Cameron A, Cappella P, Carpinelli P, Catana C, Forte B, Giordano P, Giorgini ML, Mantegani S, Marsiglio A, Meroni M, Moll J, Pittala V, Roletto F, Severino D, Soncini C, Storici P, Tonani R, Varasi M, Vulpetti A, Vianello P. Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition. J Med Chem. 2005 Apr 21;48(8):3080-4. PMID:15828847 doi:http://dx.doi.org/10.1021/jm049076m

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OCA

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