1vgn
From Proteopedia
(New page: 200px<br /><applet load="1vgn" size="450" color="white" frame="true" align="right" spinBox="true" caption="1vgn, resolution 2.63Å" /> '''Structure-based desi...) |
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| - | [[Image:1vgn.gif|left|200px]]<br /><applet load="1vgn" size=" | + | [[Image:1vgn.gif|left|200px]]<br /><applet load="1vgn" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1vgn, resolution 2.63Å" /> | caption="1vgn, resolution 2.63Å" /> | ||
'''Structure-based design of the irreversible inhibitors to metallo--lactamase (IMP-1)'''<br /> | '''Structure-based design of the irreversible inhibitors to metallo--lactamase (IMP-1)'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 1VGN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens] with ZN, OPS and ACY as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http:// | + | 1VGN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=OPS:'>OPS</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VGN OCA]. |
==Reference== | ==Reference== | ||
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[[Category: zinc]] | [[Category: zinc]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:35:11 2008'' |
Revision as of 13:35, 21 February 2008
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Structure-based design of the irreversible inhibitors to metallo--lactamase (IMP-1)
About this Structure
1VGN is a Single protein structure of sequence from Serratia marcescens with , and as ligands. Active as Beta-lactamase, with EC number 3.5.2.6 Full crystallographic information is available from OCA.
Reference
Irreversible inhibition of metallo-beta-lactamase (IMP-1) by 3-(3-mercaptopropionylsulfanyl)propionic acid pentafluorophenyl ester., Kurosaki H, Yamaguchi Y, Higashi T, Soga K, Matsueda S, Yumoto H, Misumi S, Yamagata Y, Arakawa Y, Goto M, Angew Chem Int Ed Engl. 2005 Jun 20;44(25):3861-4. PMID:15892033
Page seeded by OCA on Thu Feb 21 15:35:11 2008
Categories: Beta-lactamase | Serratia marcescens | Single protein | Arakawa, Y. | Goto, M. | Higashi, T. | Kurosaki, H. | Matsueda, S. | Misumi, S. | Soga, K. | Yamagata, Y. | Yamaguchi, Y. | ACY | OPS | ZN | Irreversible inhibitor | Metallo-beta-lactamase | Zinc
