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2hha

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Revision as of 10:53, 7 January 2013

Image:2hha.png

Template:STRUCTURE 2hha

The structure of DPP4 in complex with an oxadiazole inhibitor

Template:ABSTRACT PUBMED 16919457

About this Structure

2hha is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Xu J, Wei L, Mathvink RJ, Edmondson SD, Eiermann GJ, He H, Leone JF, Leiting B, Lyons KA, Marsilio F, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Thornberry NA, Weber AE. Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5373-7. Epub 2006 Aug 17. PMID:16919457 doi:10.1016/j.bmcl.2006.07.061

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OCA

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