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2npu

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[[Image:2npu.png|left|200px]]
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{{STRUCTURE_2npu| PDB=2npu | SCENE= }}
{{STRUCTURE_2npu| PDB=2npu | SCENE= }}
===The solution structure of the rapamycin-binding domain of mTOR (FRB)===
===The solution structure of the rapamycin-binding domain of mTOR (FRB)===
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{{ABSTRACT_PUBMED_17684489}}
{{ABSTRACT_PUBMED_17684489}}
==About this Structure==
==About this Structure==
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2NPU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPU OCA].
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[[2npu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NPU OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:17684489</ref><references group="xtra"/>
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<ref group="xtra">PMID:017684489</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bird, I.]]
[[Category: Bird, I.]]
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[[Category: Four-helix bundle]]
[[Category: Four-helix bundle]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:15:19 2009''
 

Revision as of 13:11, 7 January 2013

Template:STRUCTURE 2npu

The solution structure of the rapamycin-binding domain of mTOR (FRB)

Template:ABSTRACT PUBMED 17684489

About this Structure

2npu is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Veverka V, Crabbe T, Bird I, Lennie G, Muskett FW, Taylor RJ, Carr MD. Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR. Oncogene. 2008 Jan 24;27(5):585-95. Epub 2007 Aug 6. PMID:17684489

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