This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2o2k
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2o2k.png|left|200px]] | [[Image:2o2k.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2o2k", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2o2k| PDB=2o2k | SCENE= }} | {{STRUCTURE_2o2k| PDB=2o2k | SCENE= }} | ||
===Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N=== | ===Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17288554}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17288554 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17288554}} | {{ABSTRACT_PUBMED_17288554}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Methylcobalamin deficiency, cblG type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=156570 156570]], Cleft lip/palate, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=156570 156570]], Down syndrome, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=156570 156570]], Neural tube defects, folate-sensitive, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=156570 156570]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2o2k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O2K OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017288554</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Methionine synthase]] | [[Category: Methionine synthase]] | ||
| Line 37: | Line 22: | ||
[[Category: Beta-meander region]] | [[Category: Beta-meander region]] | ||
[[Category: C-shaped]] | [[Category: C-shaped]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Twisted anti-parallel beta sheet]] | [[Category: Twisted anti-parallel beta sheet]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:49:22 2009'' | ||
Revision as of 15:10, 7 January 2013
Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N
Template:ABSTRACT PUBMED 17288554
About this Structure
2o2k is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wolthers KR, Toogood HS, Jowitt TA, Marshall KR, Leys D, Scrutton NS. Crystal structure and solution characterization of the activation domain of human methionine synthase. FEBS J. 2007 Feb;274(3):738-50. PMID:17288554 doi:10.1111/j.1742-4658.2006.05618.x
