2pwc
From Proteopedia
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{{STRUCTURE_2pwc| PDB=2pwc | SCENE= }} | {{STRUCTURE_2pwc| PDB=2pwc | SCENE= }} | ||
===HIV-1 protease in complex with a amino decorated pyrrolidine-based inhibitor=== | ===HIV-1 protease in complex with a amino decorated pyrrolidine-based inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2pwc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PWC OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018348517</ref><references group="xtra"/> |
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Protein-ligand complex]] | [[Category: Protein-ligand complex]] | ||
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Revision as of 17:58, 7 January 2013
HIV-1 protease in complex with a amino decorated pyrrolidine-based inhibitor
Template:ABSTRACT PUBMED 18348517
About this Structure
2pwc is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Blum A, Bottcher J, Heine A, Klebe G, Diederich WE. Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold. J Med Chem. 2008 Apr 10;51(7):2078-87. Epub 2008 Mar 19. PMID:18348517 doi:10.1021/jm701142s
