3coh
From Proteopedia
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| - | + | [[Image:3coh.png|left|200px]] | |
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{{STRUCTURE_3coh| PDB=3coh | SCENE= }} | {{STRUCTURE_3coh| PDB=3coh | SCENE= }} | ||
===Crystal structure of Aurora-A in complex with a pentacyclic inhibitor=== | ===Crystal structure of Aurora-A in complex with a pentacyclic inhibitor=== | ||
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| - | (as it appears on PubMed at http://www.pubmed.gov), where 18630890 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_18630890}} | {{ABSTRACT_PUBMED_18630890}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3coh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COH OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018630890</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:07:32 2009'' | ||
Revision as of 18:04, 7 January 2013
Crystal structure of Aurora-A in complex with a pentacyclic inhibitor
Template:ABSTRACT PUBMED 18630890
About this Structure
3coh is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rawson TE, Ruth M, Blackwood E, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Georges GJ, Goller B, Halladay J, Hunsaker T, Kleinheinz T, Krell HW, Li J, Liang J, Limberg A, McNutt A, Moffat J, Phillips G, Ran Y, Safina B, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhou A, Zhu BY, Ruger P, Cochran AG. A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability. J Med Chem. 2008 Aug 14;51(15):4465-75. Epub 2008 Jul 17. PMID:18630890 doi:10.1021/jm800052b
