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3cas

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Revision as of 19:11, 7 January 2013

Image:3cas.png

Template:STRUCTURE 3cas

Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione

Template:ABSTRACT PUBMED 19075558

About this Structure

3cas is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Faucher F, Cantin L, Luu-The V, Labrie F, Breton R. Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition. Biochemistry. 2008 Dec 23;47(51):13537-46. PMID:19075558 doi:10.1021/bi801276h

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OCA

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