2r6p

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Template:STRUCTURE 2r6p

Fit of E protein and Fab 1A1D-2 into 24 angstrom resolution cryoEM map of Fab complexed with dengue 2 virus.

Template:ABSTRACT PUBMED 18264114

About this Structure

2r6p is a 7 chain structure with sequence from Dengue virus 2 puerto rico/pr159-s1/1969 and Mus musculus. The July 2008 RCSB PDB Molecule of the Month feature on Dengue Virus by David Goodsell is 10.2210/rcsb_pdb/mom_2008_7. Full crystallographic information is available from OCA.

Reference

  • Lok SM, Kostyuchenko V, Nybakken GE, Holdaway HA, Battisti AJ, Sukupolvi-Petty S, Sedlak D, Fremont DH, Chipman PR, Roehrig JT, Diamond MS, Kuhn RJ, Rossmann MG. Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nat Struct Mol Biol. 2008 Mar;15(3):312-7. Epub 2008 Feb 10. PMID:18264114 doi:10.1038/nsmb.1382

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