This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3cot
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3cot.png|left|200px]] | [[Image:3cot.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3cot", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3cot| PDB=3cot | SCENE= }} | {{STRUCTURE_3cot| PDB=3cot | SCENE= }} | ||
===Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.=== | ===Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_18407998}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 18407998 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_18407998}} | {{ABSTRACT_PUBMED_18407998}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3cot]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COT OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018407998</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Christianson, D W.]] | [[Category: Christianson, D W.]] | ||
| Line 31: | Line 19: | ||
[[Category: 5beta reductase]] | [[Category: 5beta reductase]] | ||
[[Category: Bile acid catabolism]] | [[Category: Bile acid catabolism]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: E120]] | [[Category: E120]] | ||
| Line 39: | Line 26: | ||
[[Category: Steroid c-c double bond reduction]] | [[Category: Steroid c-c double bond reduction]] | ||
[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:11:33 2009'' | ||
Revision as of 19:50, 7 January 2013
Crystal structure of human liver delta(4)-3-ketosteroid 5beta-reductase (akr1d1) in complex with progesterone and nadp. Resolution: 2.03 A.
Template:ABSTRACT PUBMED 18407998
About this Structure
3cot is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Di Costanzo L, Drury JE, Penning TM, Christianson DW. Crystal structure of human liver Delta4-3-ketosteroid 5beta-reductase (AKR1D1) and implications for substrate binding and catalysis. J Biol Chem. 2008 Jun 13;283(24):16830-9. Epub 2008 Apr 11. PMID:18407998 doi:http://dx.doi.org/10.1074/jbc.M801778200
