3dbc
From Proteopedia
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{{STRUCTURE_3dbc| PDB=3dbc | SCENE= }} | {{STRUCTURE_3dbc| PDB=3dbc | SCENE= }} | ||
===Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 257=== | ===Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 257=== | ||
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{{ABSTRACT_PUBMED_18793847}} | {{ABSTRACT_PUBMED_18793847}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3dbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBC OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018793847</ref><references group="xtra"/> |
[[Category: Danio rerio]] | [[Category: Danio rerio]] | ||
[[Category: Polo kinase]] | [[Category: Polo kinase]] | ||
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[[Category: Small-molecule inhibitor]] | [[Category: Small-molecule inhibitor]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:42:47 2009'' | ||
Revision as of 20:43, 7 January 2013
Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 257
Template:ABSTRACT PUBMED 18793847
About this Structure
3dbc is a 1 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA.
Reference
- Fucini RV, Hanan EJ, Romanowski MJ, Elling RA, Lew W, Barr KJ, Zhu J, Yoburn JC, Liu Y, Fahr BT, Fan J, Lu Y, Pham P, Choong IC, VanderPorten EC, Bui M, Purkey HE, Evanchik MJ, Yang W. Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5648-52. Epub 2008 Aug 29. PMID:18793847 doi:10.1016/j.bmcl.2008.08.095
