This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1h5n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 29: Line 29:
[[Category: reductase]]
[[Category: reductase]]
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:34:49 2007''
+
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 15:29:42 2007''

Revision as of 13:24, 30 October 2007

Image:1h5n.gif

1h5n, resolution 2.0Å

Drag the structure with the mouse to rotate

DMSO REDUCTASE MODIFIED BY THE PRESENCE OF DMS AND AIR

Overview

The bis-molybdopterin enzyme dimethylsulfoxide reductase (DMSOR) from, Rhodobacter capsulatus catalyzes the conversion of dimethyl sulfoxide, (DMSO) to dimethyl sulfide (DMS), reversibly, in the presence of suitable, e(-)-donors or e(-)-acceptors. The catalytically significant intermediate, formed by reaction of DMSOR with DMS ('the DMS species') and a damaged, enzyme form derived by reaction of the latter with O(2) (DMS-modified, enzyme, DMSOR(mod)D) have been investigated. Evidence is presented that Mo, in the DMS species is not, as widely assumed, Mo(IV). Formation of the DMS, species is reversed on removing DMS or by addition of an excess of DMSO., Equilibrium constants for the competing reactions of DMS and DMSO with the, oxidized enzyme (K(d) = 0.07 +/- 0.01 and 21 +/- 5 mM, ... [(full description)]

About this Structure

1H5N is a [Single protein] structure of sequence from [Rhodobacter capsulatus] with SO4, PGD and 6MO as [ligands]. Structure known Active Site: 6MO. Full crystallographic information is available from [OCA].

Reference

Reactions of dimethylsulfoxide reductase in the presence of dimethyl sulfide and the structure of the dimethyl sulfide-modified enzyme., Bray RC, Adams B, Smith AT, Richards RL, Lowe DJ, Bailey S, Biochemistry. 2001 Aug 21;40(33):9810-20. PMID:11502174

Page seeded by OCA on Tue Oct 30 15:29:42 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h5n"
Personal tools