3ccn

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Template:STRUCTURE 3ccn

X-ray structure of c-Met with triazolopyridazine inhibitor.

Template:ABSTRACT PUBMED 18426196

About this Structure

3ccn is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Albrecht BK, Harmange JC, Bauer D, Berry L, Bode C, Boezio AA, Chen A, Choquette D, Dussault I, Fridrich C, Hirai S, Hoffman D, Larrow JF, Kaplan-Lefko P, Lin J, Lohman J, Long AM, Moriguchi J, O'Connor A, Potashman MH, Reese M, Rex K, Siegmund A, Shah K, Shimanovich R, Springer SK, Teffera Y, Yang Y, Zhang Y, Bellon SF. Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase. J Med Chem. 2008 May 22;51(10):2879-82. Epub 2008 Apr 22. PMID:18426196 doi:10.1021/jm800043g

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OCA

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