Torpedo californica acetylcholinesterase with bifunctional inhibitor

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(New page: 200px {{STRUCTURE_2cek| PDB=2cek | SCENE= }} '''Conformational flexibility in the peripheral site of ''Torpedo californica'' acetylecholinesterase revealed by...)
Current revision (12:22, 16 January 2013) (edit) (undo)
 
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<StructureSection load='2cek' size='400' side='right' scene= caption=''>
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[[Image:2cek.gif|left|200px]]
[[Image:2cek.gif|left|200px]]
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{{STRUCTURE_2cek| PDB=2cek | SCENE= }}
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'''Conformational flexibility in the peripheral site of ''Torpedo californica'' acetylecholinesterase revealed by the complex structure with a bifunctional inhibitor ([[2cek]])'''
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'''Conformational flexibility in the peripheral site of ''Torpedo californica'' acetylecholinesterase revealed by the complex structure with a bifunctional inhibitor'''
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==Overview==
==Overview==
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==Down the gorge==
==Down the gorge==
<scene name='2cek/Down_the_gorge/2'>NF595</scene> binds both the active and peripheral sites. It is mainly bound to <scene name='2cek/Down_the_gorge_labeled/1'>Trp84 and Trp279</scene> through pi-pi interactions. The n-carbon long linker spans the gorge.
<scene name='2cek/Down_the_gorge/2'>NF595</scene> binds both the active and peripheral sites. It is mainly bound to <scene name='2cek/Down_the_gorge_labeled/1'>Trp84 and Trp279</scene> through pi-pi interactions. The n-carbon long linker spans the gorge.
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</StructureSection>
==Reference==
==Reference==
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[[Category: synapse membrane]]
[[Category: synapse membrane]]
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Created with the participation of [[User:Eran Hodis|Eran Hodis]], [[User:Jaime Prilusky|Jaime Prilusky]].
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*Created with the participation of [[User:Eran Hodis|Eran Hodis]], [[User:Jaime Prilusky|Jaime Prilusky]].

Current revision

PDB ID 2cek

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Reference

Conformational flexibility in the peripheral site of Torpedo californica acetylcholinesterase revealed by the complex structure with a bifunctional inhibitor., Colletier JP, Sanson B, Nachon F, Gabellieri E, Fattorusso C, Campiani G, Weik M, J Am Chem Soc. 2006 Apr 12;128(14):4526-7. PMID:16594661

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Jaime Prilusky

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