1xha

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[[Image:1xha.png|left|200px]]
[[Image:1xha.png|left|200px]]
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{{STRUCTURE_1xha| PDB=1xha | SCENE= }}
{{STRUCTURE_1xha| PDB=1xha | SCENE= }}
===Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants===
===Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants===
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{{ABSTRACT_PUBMED_15634010}}
{{ABSTRACT_PUBMED_15634010}}
==About this Structure==
==About this Structure==
[[1xha]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XHA OCA].
[[1xha]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XHA OCA].
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==See Also==
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*[[CAMP-dependent protein kinase|CAMP-dependent protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:15634010</ref><ref group="xtra">PMID:14998327</ref><references group="xtra"/>
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<ref group="xtra">PMID:015634010</ref><ref group="xtra">PMID:014998327</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Pka]]
[[Category: Pka]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase/transferase inhibitor complex]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 12:30, 23 January 2013

Template:STRUCTURE 1xha

Contents

Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants

Template:ABSTRACT PUBMED 15634010

About this Structure

1xha is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  • Breitenlechner CB, Friebe WG, Brunet E, Werner G, Graul K, Thomas U, Kunkele KP, Schafer W, Gassel M, Bossemeyer D, Huber R, Engh RA, Masjost B. Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants. J Med Chem. 2005 Jan 13;48(1):163-70. PMID:15634010 doi:http://dx.doi.org/10.1021/jm049701n
  • Breitenlechner CB, Wegge T, Berillon L, Graul K, Marzenell K, Friebe WG, Thomas U, Schumacher R, Huber R, Engh RA, Masjost B. Structure-based optimization of novel azepane derivatives as PKB inhibitors. J Med Chem. 2004 Mar 11;47(6):1375-90. PMID:14998327 doi:http://dx.doi.org/10.1021/jm0310479

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