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Template:STRUCTURE 1prh

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{{Structure
{{Structure
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1prh]], resolution 3.50&Aring; (<scene name='initialview01'>default scene</scene>)}}}
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|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1prh]], [[Resolution|resolution]] 3.50&Aring; (<scene name='initialview01'>default scene</scene>)}}}
|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>
|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam03098 An_peroxidase], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054 EGF_CA]</span>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] </span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1prh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1prh OCA], [http://www.ebi.ac.uk/pdbsum/1prh PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1prh RCSB]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1prh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1prh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1prh RCSB], [http://www.ebi.ac.uk/pdbsum/1prh PDBsum]</span>
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|FUNCTION={{GO|id=GO:0004666 | text = prostaglandin-endoperoxide synthase activity}}{{GO|id=GO:0004601 | text = peroxidase activity}}{{GO|id=GO:0005506 | text = iron ion binding}}{{GO|id=GO:0016702 | text = oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0016491 | text = oxidoreductase activity}}{{GO|id=GO:0020037 | text = heme binding}}
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|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/domain/1prhA02 1Prha02], [http://www.cathdb.info/domain/1prhA01 1Prha01], [http://www.cathdb.info/domain/1prhB02 1Prhb02], [http://www.cathdb.info/domain/1prhB01 1Prhb01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010255 Ipr010255], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000742 Ipr000742], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006210 Ipr006210], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR019791 Ipr019791], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002007 Ipr002007]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF03098 PF03098]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=18710 d1prha1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=44253 d1prha2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=18711 d1prhb1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=44254 d1prhb2]</span>
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|PROCESS={{GO|id=GO:0006979 | text = response to oxidative stress}}{{GO|id=GO:0006118 | text = electron transport}}{{GO|id=GO:0008610 | text = lipid biosynthetic process}}{{GO|id=GO:0006633 | text = fatty acid biosynthetic process}}{{GO|id=GO:0008217 | text = regulation of blood pressure}}{{GO|id=GO:0001516 | text = prostaglandin biosynthetic process}}
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|uPDB=1PRH|CONSURF={{!}}-
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|COMPONENT={{GO|id=GO:0005792 | text = microsome}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0005737 | text = cytoplasm}}{{GO|id=GO:0005783 | text = endoplasmic reticulum}}{{GO|id=GO:0016021 | text = integral to membrane}}
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|SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1prhA02 1Prha02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1prhA01 1Prha01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1prhB02 1Prhb02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1prhB01 1Prhb01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000742 Ipr000742], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010255 Ipr010255], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013032 Ipr013032], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006210 Ipr006210], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002007 Ipr002007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006209 Ipr006209]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00008 PF00008], [http://pfam.sanger.ac.uk/family?acc=PF03098 PF03098]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=44253 d1prha2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=18710 d1prha1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=44254 d1prhb2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=18711 d1prhb1]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P05979 P05979]</span>
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|CONSURF={{!}}-
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{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Current revision

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1prh, resolution 3.50Å ()
Ligands:
Activity: Prostaglandin-endoperoxide synthase, with EC number 1.14.99.1
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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