Gramicidin

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== 3D Structures of Gramicidin ==
== 3D Structures of Gramicidin ==
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''Update November 2011''
+
''Update February 2013''
===Gramicidin A===
===Gramicidin A===
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[[2xdc]], [[1w5u]], [[1bdw]], [[1al4]], [[1alx]], [[1alz]], [[2y5m]], [[2y6n]] – GCDN D<br />
[[2xdc]], [[1w5u]], [[1bdw]], [[1al4]], [[1alx]], [[1alz]], [[2y5m]], [[2y6n]] – GCDN D<br />
[[3lml]], [[2izq]], [[3i8i]], [[3l8l]] - GCDN D + iodide<br />
[[3lml]], [[2izq]], [[3i8i]], [[3l8l]] - GCDN D + iodide<br />
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[[1c4d]] - GCDN D + CsCl
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[[1c4d]] - GCDN D + CsCl<br />
 +
[[3zq8]] – GCDN D + monovaccenin
===Gramicidin S===
===Gramicidin S===

Revision as of 11:36, 4 February 2013

Image:2xdc.png
Crystal Structure of Gramicidin, 2xdc

Gramicidin D dimer with formyl-valine, formyl-isoleucine complex with propanol and ethanolamine , 1al4

Drag the structure with the mouse to rotate












Gramicidin (GCDN) is a polypeptide composed of alternating L- and D-amino acids. It has bactericidal activity and is used as antibiotic. It is produced by the bacteria Bacillus brevis. GCDN S is a cyclic polypeptide. GCDN D is a mixture of GCDN A, B, C. GCDN S is an antibiotic. See theoretical model of Gramicidin Channel in Lipid Bilayer.

Contents




3D Structures of Gramicidin

Update February 2013

Gramicidin A

1nt5, 1nt6, 1nrm, 1nru, 1ng8, 1kqe, 1jno, 1jo3, 1jo4, 1mic, 1mag, 1grm - GCDN A – NMR
1tkq - GCDN A + mini-GCDN A – NMR
1av2 - GCDN A + CsCl
1gmk - GCDN A + KCNS

Gramicidin D

2xdc, 1w5u, 1bdw, 1al4, 1alx, 1alz, 2y5m, 2y6n – GCDN D
3lml, 2izq, 3i8i, 3l8l - GCDN D + iodide
1c4d - GCDN D + CsCl
3zq8 – GCDN D + monovaccenin

Gramicidin S

1tk2 – GCDN S + subtilisin savinase – Bacillus lentus

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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