Peroxiredoxin
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1qq2.png|left|200px|thumb|Crystal Structure of Peroxiredoxin ([[1qq2]])]] | [[Image:1qq2.png|left|200px|thumb|Crystal Structure of Peroxiredoxin ([[1qq2]])]] | ||
| - | {{STRUCTURE_1qq2| PDB=1qq2 | SIZE=400| SCENE= |right|CAPTION=Peroxiredoxin dimer complex with Cl ions [[1qq2]]}} | + | {{STRUCTURE_1qq2| PDB=1qq2 | SIZE=400| SCENE= |right|CAPTION=Peroxiredoxin dimer complex with Cl- ions [[1qq2]]}} |
| Line 34: | Line 34: | ||
== 3D Structures of Peroxiredoxin == | == 3D Structures of Peroxiredoxin == | ||
| - | ''Updated | + | ''Updated February 2013'' |
[[1qq2]] – 2Cys-Prx – rat<br /> | [[1qq2]] – 2Cys-Prx – rat<br /> | ||
| Line 58: | Line 58: | ||
[[1tp9]] – Prx II – ''Populus trichocarpa''<br /> | [[1tp9]] – Prx II – ''Populus trichocarpa''<br /> | ||
[[2pwj]] – Prx II – garden pea<br /> | [[2pwj]] – Prx II – garden pea<br /> | ||
| - | [[4dsq]], [[4dsr]] – yPrx II<br /> | + | [[4g2e]] – Prx – ''Sulfolobus tokodaii''<br /> |
| + | [[4dsq]], [[4dsr]], [[4h86]] – yPrx II<br /> | ||
| + | [[3sbc]] – yPrx Tsa1 (mutant)<br /> | ||
[[4dss]] – yPrx II (mutant) + thioredoxin II<br /> | [[4dss]] – yPrx II (mutant) + thioredoxin II<br /> | ||
[[1uul]] - 2Cys-Prx – ''Trypanosoma cruzi''<br /> | [[1uul]] - 2Cys-Prx – ''Trypanosoma cruzi''<br /> | ||
Revision as of 11:14, 10 February 2013
Peroxiredoxin (Prx) is an antioxidant enzyme. In the Prxs the active-site Cys is oxidized to sulfenic acid byperoxide. The Prxs are divided into typical 2-Cys Prx, atypical 2-Cys Prx and 1-Cys Prx. Prx 5 is expressed in mammalian tissue. The images at the left and at the right correspond to one representative Prx, i.e. the crystal structure of Peroxiredoxin from rat (1qq2).
Contents |
3D Structures of Peroxiredoxin
Updated February 2013
1qq2 – 2Cys-Prx – rat
2c0d – Pf2Cys-Prx – Plasmodium falciparum
1xiy – Pf1Cys-Prx
1xcc, 2h01, 3tb2 - 1Cys-Prx – Plasmodium yoelii
2i81 - 2Cys-Prx – Plasmodium vivax
1qmv - h2Cys-Prx – human
2rii, 3hy2 – hPrx 1 (mutant)+sulfiredoxin 1
2z9s – Prx 1 (mutant) - rat
3tjf, 3tjg, 3tjj, 3tjk, 3tkr - hPrx 4 (mutant)
3qpm – Prx 4 – Larimichtys crocea
2pn8, 3tjb, 3tkp, 3tkq, 3tks – hPrx 4
1urm – hPrx 5 (mutant) – human
2vl2, 2vl3, 2vl9, 1h4o, 1hd2, 1oc3 – hPrx 5
3mng – hPrx 5+DTT
2wfc – lPrx 5 - lugworm
2xhf – Prx 5 – Alvinella pompejana
2v2g – lPrx 6
2v32, 2v41 – lPrx 6 (mutant)
2a4v – yPrx dot5 C-termianl (mutant) – yeast
3cmi – yPrx hyr1
1tp9 – Prx II – Populus trichocarpa
2pwj – Prx II – garden pea
4g2e – Prx – Sulfolobus tokodaii
4dsq, 4dsr, 4h86 – yPrx II
3sbc – yPrx Tsa1 (mutant)
4dss – yPrx II (mutant) + thioredoxin II
1uul - 2Cys-Prx – Trypanosoma cruzi
1we0 – Prx – Amphibacillus xylanus
1zye – Prx III (mutant) – bovine
2cv4, 2cx3, 2cx4 – Prx – Aeropyrum pernix
3drn – SsPrx – Sulfolobus solfataricus
3hjp – SsPrx (mutant)
3ixr – Prx PRXQ (mutant) – Xylella fastidiosa
