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3fcs
From Proteopedia
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[[Image:3fcs.png|left|200px]] | [[Image:3fcs.png|left|200px]] | ||
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{{STRUCTURE_3fcs| PDB=3fcs | SCENE= }} | {{STRUCTURE_3fcs| PDB=3fcs | SCENE= }} | ||
===Structure of complete ectodomain of integrin aIIBb3=== | ===Structure of complete ectodomain of integrin aIIBb3=== | ||
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{{ABSTRACT_PUBMED_19111664}} | {{ABSTRACT_PUBMED_19111664}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Glanzmann thrombasthenia, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]], Thrombocytopenia, neonatal alloimmune OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607759 607759]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3fcs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The February 2011 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Integrin'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2011_2 10.2210/rcsb_pdb/mom_2011_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCS OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019111664</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| + | [[Category: Integrin]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Luo, B H.]] | [[Category: Luo, B H.]] | ||
[[Category: Nishida, N.]] | [[Category: Nishida, N.]] | ||
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[[Category: Zhang, C.]] | [[Category: Zhang, C.]] | ||
[[Category: Zhu, J.]] | [[Category: Zhu, J.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Beta propeller]] | [[Category: Beta propeller]] | ||
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
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[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Rossmann fold]] | [[Category: Rossmann fold]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 14:57:30 2010'' | ||
Revision as of 11:06, 13 February 2013
Structure of complete ectodomain of integrin aIIBb3
Template:ABSTRACT PUBMED 19111664
About this Structure
3fcs is a 4 chain structure with sequence from Homo sapiens. The February 2011 RCSB PDB Molecule of the Month feature on Integrin by David Goodsell is 10.2210/rcsb_pdb/mom_2011_2. Full crystallographic information is available from OCA.
Reference
- Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell. 2008 Dec 26;32(6):849-61. PMID:19111664 doi:10.1016/j.molcel.2008.11.018
Categories: Homo sapiens | Integrin | RCSB PDB Molecule of the Month | Luo, B H. | Nishida, N. | Springer, T A. | Xiao, T. | Zhang, C. | Zhu, J. | Beta propeller | Cell adhesion | Cell adhesion-blood clotting complex | Cell adhesion-immune system complex | Disease mutation | Egf domain | Glycoprotein | Host-virus interaction | Membrane | Phosphoprotein | Receptor | Rossmann fold | Transmembrane
