3g1m
From Proteopedia
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[[Image:3g1m.png|left|200px]] | [[Image:3g1m.png|left|200px]] | ||
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{{STRUCTURE_3g1m| PDB=3g1m | SCENE= }} | {{STRUCTURE_3g1m| PDB=3g1m | SCENE= }} | ||
===EthR from Mycobacterium tuberculosis in complex with compound BDM31381=== | ===EthR from Mycobacterium tuberculosis in complex with compound BDM31381=== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019412174</ref><ref group="xtra">PMID:016243584</ref><ref group="xtra">PMID:015494316</ref><ref group="xtra">PMID:014651620</ref><references group="xtra"/> |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Aumercier, M.]] | [[Category: Aumercier, M.]] | ||
Revision as of 14:45, 20 February 2013
EthR from Mycobacterium tuberculosis in complex with compound BDM31381
Template:ABSTRACT PUBMED 19412174
About this Structure
3g1m is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Willand N, Dirie B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Deprez-Poulain R, Delcroix G, Frenois F, Aumercier M, Locht C, Villeret V, Deprez B, Baulard AR. Synthetic EthR inhibitors boost antituberculous activity of ethionamide. Nat Med. 2009 May;15(5):537-44. Epub 2009 May 3. PMID:19412174 doi:10.1038/nm.1950
- Frenois F, Baulard AR, Villeret V. Insights into mechanisms of induction and ligands recognition in the transcriptional repressor EthR from Mycobacterium tuberculosis. Tuberculosis (Edinb). 2006 Mar;86(2):110-4. Epub 2005 Oct 21. PMID:16243584 doi:10.1016/j.tube.2005.07.005
- Frenois F, Engohang-Ndong J, Locht C, Baulard AR, Villeret V. Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis. Mol Cell. 2004 Oct 22;16(2):301-7. PMID:15494316 doi:10.1016/j.molcel.2004.09.020
- Engohang-Ndong J, Baillat D, Aumercier M, Bellefontaine F, Besra GS, Locht C, Baulard AR. EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator. Mol Microbiol. 2004 Jan;51(1):175-88. PMID:14651620
Categories: Mycobacterium tuberculosis | Aumercier, M. | Baulard, A R. | Bifani, P. | Carette, X. | Delcroix, G. | Deprez, B. | Deprez-Poulain, R. | Desroses, M. | Dirie, B. | Frenois, F. | Leroux, F. | Locht, C. | Mathys, V. | Singhal, A. | Villeret, V. | Willand, N. | Willery, E. | Dna-binding | Tetr family | Transcription | Transcription regulation
