Barstar

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'''Barstar''' (BST) is an inhibitor synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.
'''Barstar''' (BST) is an inhibitor synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.
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Revision as of 14:08, 6 March 2013

Image:2hxx.png
Crystal Structure of Barstar 2hxx

Template:STRUCTURE 1a19











Barstar (BST) is an inhibitor synthesized and secreted by the bacterium Bacillus amyloliquefaciens. It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.





3D Structures of Barstar

2hxx, 2cx6 – BST
1a19 – BST (mutant)
1l1k, 1bta, 1btb – BST – NMR
1ab7 - BST (mutant) - NMR

BST + BA

3da7 – BST + BA (mutant)
2za4, 1brs, 1bgs – BST + BA
1x1u, 1x1w, 1x1x, 1x1y, 1b27, 1b2u – BST (mutant) + BA
1b3s, 1b2s - BST (mutant) + BA (mutant)
1ay7 – BST + guanyl-specific RNase SA – Streptomyces aureofaciens

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Michal Harel, Alexander Berchansky

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