Glutathione peroxidase
From Proteopedia
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== 3D Structures of glutathione peroxidase == | == 3D Structures of glutathione peroxidase == | ||
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===GPX1=== | ===GPX1=== |
Revision as of 08:38, 10 March 2013
Glutathione peroxidase (GPX) reduces lipid hydroperoxides to alcohols and free hydrogen peroxide to water. Thus, GPX protects the organism from oxidative damage. There are several isozymes of GPX. Eight isozymes have been found in human. GPX1 is found in the cytoplasm and reduces hydrogen peroxide. GPX2 is intestinal and extracellular. GPX3 is abundant in plasma. GPX4 substrate is lipid hydroxyperoxide.
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3D Structures of glutathione peroxidase
Updated on 10-March-2013
GPX1
2f8a – hGPX1 (mutant) – human
3e0u – GPX1 – Trypanosoma cruzi
GPX2
2he3 – hGPX2 (mutant)
GPX3
2r37 – hGPX3 (mutant) 3cmi – GPX3 – yeast
GPX4
GPX5
2i3y – hGPX5
GPX7
2p31 – hGPX7
GPX8
3cyn – hGPX8
GPX
1gp1 – GPX + amino-selenino-propionic acid – bovine
2v1m – SmGPX – Schistosoma mansoni
2wgr – SmGPX (mutant)