This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Template:STRUCTURE 1x70
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{ | + | {{Structure |
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1x70, resolution 2.10Å (<scene name='initialview01'> | + | |PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1x70]], [[Resolution|resolution]] 2.10Å (<scene name='initialview01'>default scene</scene>)}}} |
| - | |LIGAND= <scene name='pdbligand=715:(2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE'>715</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG: | + | |LIGAND= <scene name='pdbligand=715:(2R)-4-OXO-4-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE'>715</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene> |
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] </span> | ||
|GENE= DPP4, ADCP2, CD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= DPP4, ADCP2, CD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| - | + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x70 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1x70 RCSB], [http://www.ebi.ac.uk/pdbsum/1x70 PDBsum]</span> | |
| - | + | |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/domain/1x70A01 1X70A01], [http://www.cathdb.info/domain/1x70A02 1X70A02], [http://www.cathdb.info/domain/1x70B02 1X70B02], [http://www.cathdb.info/domain/1x70B01 1X70B01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002469 Ipr002469], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002471 Ipr002471], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001375 Ipr001375]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00930 PF00930], [http://pfam.sanger.ac.uk/family?acc=PF00326 PF00326]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=121765 d1x70a2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=121764 d1x70a1], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=121767 d1x70b2], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=121766 d1x70b1]</span> | |
| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x70 OCA], [http://www. | + | |uPDB=1X70|CONSURF={{!}}- |
| - | + | {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]] | |
| - | + | {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" | |
| - | + | {{!}} '''Toggle Conservation Colors:''' | |
| - | |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/ | + | {{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}} |
| - | + | Rows = identical sequences: | |
| + | <jmol> | ||
| + | <jmolButton> | ||
| + | <script></script> | ||
| + | <text>A [x]</text> | ||
| + | <name>jmb_1x70_A</name> | ||
| + | <title>toggle chain A</title> | ||
| + | <jsscript>ConsurfChainButton(elementClicked)</jsscript> | ||
| + | <appendtargetsuffixtoid>true</appendtargetsuffixtoid> | ||
| + | </jmolButton> | ||
| + | </jmol> | ||
| + | <jmol> | ||
| + | <jmolButton> | ||
| + | <script></script> | ||
| + | <text>B [x]</text> | ||
| + | <name>jmb_1x70_B</name> | ||
| + | <title>toggle chain B</title> | ||
| + | <jsscript>ConsurfChainButton(elementClicked)</jsscript> | ||
| + | <appendtargetsuffixtoid>true</appendtargetsuffixtoid> | ||
| + | </jmolButton> | ||
| + | </jmol> | ||
| + | |||
}} | }} | ||
Current revision
| |||||||||
| 1x70, resolution 2.10Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , , | ||||||||
| Gene: | DPP4, ADCP2, CD26 (Homo sapiens) | ||||||||
| Activity: | Dipeptidyl-peptidase IV, with EC number 3.4.14.5 | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
