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Template:STRUCTURE 2hyy

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Current revision (09:25, 11 March 2013) (edit) (undo)
 
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|GENE= ABL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= ABL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|RELATEDENTRY=[[1iep|1iep]], [[1fpu|1fpu]]
|RELATEDENTRY=[[1iep|1iep]], [[1fpu|1fpu]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hyy OCA], [http://www.ebi.ac.uk/pdbsum/2hyy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hyy RCSB]</span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hyy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hyy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hyy RCSB], [http://www.ebi.ac.uk/pdbsum/2hyy PDBsum]</span>
|FUNCTION={{GO|id=GO:0005524 | text = ATP binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0004713 | text = protein-tyrosine kinase activity}}{{GO|id=GO:0008022 | text = protein C-terminus binding}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0030145 | text = manganese ion binding}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0004672 | text = protein kinase activity}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0046872 | text = metal ion binding}}
|FUNCTION={{GO|id=GO:0005524 | text = ATP binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0004713 | text = protein-tyrosine kinase activity}}{{GO|id=GO:0008022 | text = protein C-terminus binding}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0030145 | text = manganese ion binding}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0004672 | text = protein kinase activity}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0046872 | text = metal ion binding}}
|PROCESS={{GO|id=GO:0030036 | text = actin cytoskeleton organization and biogenesis}}{{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0018108 | text = peptidyl-tyrosine phosphorylation}}{{GO|id=GO:0007242 | text = intracellular signaling cascade}}{{GO|id=GO:0006298 | text = mismatch repair}}{{GO|id=GO:0008630 | text = DNA damage response, signal transduction resulting in induction of apoptosis}}{{GO|id=GO:0000115 | text = S-phase-specific transcription in mitotic cell cycle}}{{GO|id=GO:0006355 | text = regulation of transcription, DNA-dependent}}{{GO|id=GO:0007155 | text = cell adhesion}}{{GO|id=GO:0006464 | text = protein modification process}}
|PROCESS={{GO|id=GO:0030036 | text = actin cytoskeleton organization and biogenesis}}{{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0018108 | text = peptidyl-tyrosine phosphorylation}}{{GO|id=GO:0007242 | text = intracellular signaling cascade}}{{GO|id=GO:0006298 | text = mismatch repair}}{{GO|id=GO:0008630 | text = DNA damage response, signal transduction resulting in induction of apoptosis}}{{GO|id=GO:0000115 | text = S-phase-specific transcription in mitotic cell cycle}}{{GO|id=GO:0006355 | text = regulation of transcription, DNA-dependent}}{{GO|id=GO:0007155 | text = cell adhesion}}{{GO|id=GO:0006464 | text = protein modification process}}

Current revision

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2hyy, resolution 2.40Å ()
Ligands:
Gene: ABL1 (Homo sapiens)
Activity: Non-specific protein-tyrosine kinase, with EC number 2.7.10.2
Related: 1iep, 1fpu
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


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