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Template:STRUCTURE 2oxu

From Proteopedia

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Current revision

2oxu, resolution 1.24Å ()

Ligands:

Gene:

MMP12, HME (Homo sapiens)

Activity:

Macrophage elastase, with EC number 3.4.24.65

Related:

1y93, 1rmz, 2oxw, 2oxz, 2oy2, 2oy4

Structural annotation:
Resources:	InterPro : Ipr000585, Ipr006025, Ipr002477, Ipr001818, Ipr006026 Pfam : PF00413 UniProt : P39900

Functional annotation:
Cellular component:	proteinaceous extracellular matrix
Biological process:	metabolic process proteolysis cell motility
Molecular function:	metallopeptidase activity catalytic activity metal ion binding macrophage elastase activity peptidase activity hydrolase activity metalloendopeptidase activity calcium ion binding zinc ion binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_2oxu"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|2oxu, resolution 1.24&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2oxu]], [[Resolution|resolution]] 1.24&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span>
 |GENE= MMP12, HME ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04278 ZnMc_MMP]</span>
+|RELATEDENTRY=[[1y93|1y93]], [[1rmz|1rmz]], [[2oxw|2oxw]], [[2oxz|2oxz]], [[2oy2|2oy2]], [[2oy4|2oy4]]
-|RELATEDENTRY=[[1y93|1y93]], [[1rmz|1rmz]]
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oxu RCSB], [http://www.ebi.ac.uk/pdbsum/2oxu PDBsum]</span>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxu OCA], [http://www.ebi.ac.uk/pdbsum/2oxu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2oxu RCSB]</span>
 |FUNCTION={{GO|id=GO:0008237 | text = metallopeptidase activity}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0004234 | text = macrophage elastase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0004222 | text = metalloendopeptidase activity}}{{GO|id=GO:0005509 | text = calcium ion binding}}{{GO|id=GO:0008270 | text = zinc ion binding}}
 |PROCESS={{GO|id=GO:0008152 | text = metabolic process}}{{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0006928 | text = cell motility}}
 |COMPONENT={{GO|id=GO:0005578 | text = proteinaceous extracellular matrix}}
 |SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000585 Ipr000585], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006025 Ipr006025], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002477 Ipr002477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001818 Ipr001818], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006026 Ipr006026]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00413 PF00413]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P39900 P39900]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P39900 P39900]</span>
+|uPDB=2OXU|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_2oxu_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 2oxu

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