Template:STRUCTURE 2oxu
From Proteopedia
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{{Structure | {{Structure | ||
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2oxu]], resolution 1.24Å (<scene name='initialview01'>default scene</scene>)}}} | + | |PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2oxu]], [[Resolution|resolution]] 1.24Å (<scene name='initialview01'>default scene</scene>)}}} |
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | ||
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span> | ||
|GENE= MMP12, HME ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= MMP12, HME ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| - | + | |RELATEDENTRY=[[1y93|1y93]], [[1rmz|1rmz]], [[2oxw|2oxw]], [[2oxz|2oxz]], [[2oy2|2oy2]], [[2oy4|2oy4]] | |
| - | |RELATEDENTRY=[[1y93|1y93]], [[1rmz|1rmz]] | + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oxu RCSB], [http://www.ebi.ac.uk/pdbsum/2oxu PDBsum]</span> |
| - | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxu OCA], [http://www. | + | |
|FUNCTION={{GO|id=GO:0008237 | text = metallopeptidase activity}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0004234 | text = macrophage elastase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0004222 | text = metalloendopeptidase activity}}{{GO|id=GO:0005509 | text = calcium ion binding}}{{GO|id=GO:0008270 | text = zinc ion binding}} | |FUNCTION={{GO|id=GO:0008237 | text = metallopeptidase activity}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0004234 | text = macrophage elastase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0004222 | text = metalloendopeptidase activity}}{{GO|id=GO:0005509 | text = calcium ion binding}}{{GO|id=GO:0008270 | text = zinc ion binding}} | ||
|PROCESS={{GO|id=GO:0008152 | text = metabolic process}}{{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0006928 | text = cell motility}} | |PROCESS={{GO|id=GO:0008152 | text = metabolic process}}{{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0006928 | text = cell motility}} | ||
|COMPONENT={{GO|id=GO:0005578 | text = proteinaceous extracellular matrix}} | |COMPONENT={{GO|id=GO:0005578 | text = proteinaceous extracellular matrix}} | ||
|SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000585 Ipr000585], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006025 Ipr006025], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002477 Ipr002477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001818 Ipr001818], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006026 Ipr006026]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00413 PF00413]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P39900 P39900]</span> | |SARESOURCES=<span class='plainlinks'>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000585 Ipr000585], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006025 Ipr006025], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002477 Ipr002477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001818 Ipr001818], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006026 Ipr006026]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00413 PF00413]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P39900 P39900]</span> | ||
| - | | | + | |uPDB=2OXU|CONSURF={{!}}- |
| - | |CONSURF={{!}}- | + | |
{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]] | {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]] | ||
{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" | {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" | ||
Current revision
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| 2oxu, resolution 1.24Å () | |||||||||
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| Ligands: | , | ||||||||
| Gene: | MMP12, HME (Homo sapiens) | ||||||||
| Activity: | Macrophage elastase, with EC number 3.4.24.65 | ||||||||
| Related: | 1y93, 1rmz, 2oxw, 2oxz, 2oy2, 2oy4 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
