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Template:STRUCTURE 2clt

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Current revision

2clt, resolution 2.67Å ()

Ligands:

Activity:

Interstitial collagenase, with EC number 3.4.24.7

Related:

1ayk, 1cge, 1cgf, 1cgl, 1hfc, 1su3, 2ayk, 2tcl, 3ayk, 4ayk, 966c

Structural annotation:
Resources:	CATH : 2Clta02, 2Clta01, 2Cltb01, 2Cltb02 InterPro : Ipr002477, Ipr001818, Ipr006026, Ipr000585, Ipr006025 Pfam : PF00045, PF00413 UniProt : P03956

Functional annotation:
Cellular component:	proteinaceous extracellular matrix extracellular space
Biological process:	metabolic process collagen catabolic process proteolysis
Molecular function:	zinc ion binding hydrolase activity peptidase activity metal ion binding catalytic activity calcium ion binding collagenase activity metallopeptidase activity interstitial collagenase activity metalloendopeptidase activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_2clt"

@@ Line 1: / Line 1: @@
-{{StructureD
+{{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|2clt, resolution 2.67&Aring; (<scene name='initialview01'>initial scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[2clt]], [[Resolution|resolution]] 2.67&Aring; (<scene name='initialview01'>default scene</scene>)}}}
-|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Chain+B'>AC1</scene>
 |LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Interstitial_collagenase Interstitial collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.7 3.4.24.7] </span>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00094 HX], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04278 ZnMc_MMP]</span>
+|RELATEDENTRY=[[1ayk|1ayk]], [[1cge|1cge]], [[1cgf|1cgf]], [[1cgl|1cgl]], [[1hfc|1hfc]], [[1su3|1su3]], [[2ayk|2ayk]], [[2tcl|2tcl]], [[3ayk|3ayk]], [[4ayk|4ayk]], [[966c|966c]]
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2clt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2clt OCA], [http://www.ebi.ac.uk/pdbsum/2clt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2clt RCSB]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2clt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2clt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2clt RCSB], [http://www.ebi.ac.uk/pdbsum/2clt PDBsum]</span>
 |FUNCTION={{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0005509 | text = calcium ion binding}}{{GO|id=GO:0008133 | text = collagenase activity}}{{GO|id=GO:0008237 | text = metallopeptidase activity}}{{GO|id=GO:0004232 | text = interstitial collagenase activity}}{{GO|id=GO:0004222 | text = metalloendopeptidase activity}}
 |PROCESS={{GO|id=GO:0008152 | text = metabolic process}}{{GO|id=GO:0030574 | text = collagen catabolic process}}{{GO|id=GO:0006508 | text = proteolysis}}
 |COMPONENT={{GO|id=GO:0005578 | text = proteinaceous extracellular matrix}}{{GO|id=GO:0005615 | text = extracellular space}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltA02 2Clta02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltA01 2Clta01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltB01 2Cltb01], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=2cltB02 2Cltb02]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002477 Ipr002477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001818 Ipr001818], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006026 Ipr006026], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000585 Ipr000585], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR006025 Ipr006025]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00045 PF00045], [http://pfam.sanger.ac.uk/family?acc=PF00413 PF00413]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P03956 P03956]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P03956 P03956]</span>
+|uPDB=2CLT|CONSURF={{!}}-
+{{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
+{{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"
+{{!}} '''Toggle Conservation Colors:'''
+{{!}} align="left" style="background-color:#acfaac;border-top:2px solid #dddddd; border-right:2px solid #dddddd" {{!}}
+Rows = identical sequences:
+<jmol>
+<jmolButton>
+<script></script>
+<text>A [x]</text>
+<name>jmb_2clt_A</name>
+<title>toggle chain A</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
+<jmol>
+<jmolButton>
+<script></script>
+<text>B [x]</text>
+<name>jmb_2clt_B</name>
+<title>toggle chain B</title>
+<jsscript>ConsurfChainButton(elementClicked)</jsscript>
+<appendtargetsuffixtoid>true</appendtargetsuffixtoid>
+</jmolButton>
+</jmol>
 }}

Template:STRUCTURE 2clt

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