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3ugx
From Proteopedia
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{{STRUCTURE_3ugx| PDB=3ugx | SCENE= }} | {{STRUCTURE_3ugx| PDB=3ugx | SCENE= }} | ||
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===Crystal Structure of Visual Arrestin=== | ===Crystal Structure of Visual Arrestin=== | ||
| + | {{ABSTRACT_PUBMED_22306737}} | ||
| + | ==Disease== | ||
| + | [[http://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Note=S-antigen induces autoimmune uveitis. | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/ARRS_BOVIN ARRS_BOVIN]] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:022306737</ref><references group="xtra"/> | + | <ref group="xtra">PMID:022306737</ref><references group="xtra"/><references/> |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Batra-Safferling, R.]] | [[Category: Batra-Safferling, R.]] | ||
Revision as of 16:47, 24 March 2013
Contents |
Crystal Structure of Visual Arrestin
Template:ABSTRACT PUBMED 22306737
Disease
[ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis.
Function
[ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
About this Structure
3ugx is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Granzin J, Cousin A, Weirauch M, Schlesinger R, Buldt G, Batra-Safferling R. Crystal Structure of p44, a Constitutively Active Splice Variant of Visual Arrestin. J Mol Biol. 2012 Mar 9;416(5):611-8. Epub 2012 Jan 27. PMID:22306737 doi:10.1016/j.jmb.2012.01.028
