1h27
From Proteopedia
(Difference between revisions)
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| - | [[Image:1h27.png|left|200px]] | ||
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{{STRUCTURE_1h27| PDB=1h27 | SCENE= }} | {{STRUCTURE_1h27| PDB=1h27 | SCENE= }} | ||
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===CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P27=== | ===CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P27=== | ||
| + | {{ABSTRACT_PUBMED_12501191}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/CCNA2_HUMAN CCNA2_HUMAN]] Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012501191</ref><ref group="xtra">PMID:010559988</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012501191</ref><ref group="xtra">PMID:010559988</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Brown, N R.]] | [[Category: Brown, N R.]] | ||
Revision as of 17:25, 24 March 2013
Contents |
CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P27
Template:ABSTRACT PUBMED 12501191
Function
[CCNA2_HUMAN] Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
About this Structure
1h27 is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lowe ED, Tews I, Cheng KY, Brown NR, Gul S, Noble ME, Gamblin SJ, Johnson LN. Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A. Biochemistry. 2002 Dec 31;41(52):15625-34. PMID:12501191
- Brown NR, Noble ME, Endicott JA, Johnson LN. The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Nat Cell Biol. 1999 Nov;1(7):438-43. PMID:10559988 doi:10.1038/15674
Categories: Homo sapiens | Brown, N R. | Cheng, K Y. | Gamblin, S. | Gul, S. | Johnson, L N. | Lowe, E D. | Noble, M E.M. | Tews, I. | Atp-binding | Cdk2 | Cell cycle | Cell division | Cyclin | Hydrolase-hydrolase inhibitor complex | Mitosis | Peptide specificity | Phosphorylation | Protein kinase | Recruitment | Serine/threonine-protein kinase
