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1h27

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[[Image:1h27.png|left|200px]]
 
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{{STRUCTURE_1h27| PDB=1h27 | SCENE= }}
{{STRUCTURE_1h27| PDB=1h27 | SCENE= }}
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===CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P27===
===CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P27===
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{{ABSTRACT_PUBMED_12501191}}
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{{ABSTRACT_PUBMED_12501191}}
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==Function==
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[[http://www.uniprot.org/uniprot/CCNA2_HUMAN CCNA2_HUMAN]] Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:012501191</ref><ref group="xtra">PMID:010559988</ref><references group="xtra"/>
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<ref group="xtra">PMID:012501191</ref><ref group="xtra">PMID:010559988</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Brown, N R.]]
[[Category: Brown, N R.]]

Revision as of 17:25, 24 March 2013

Template:STRUCTURE 1h27

Contents

CDK2/CYCLIN A IN COMPLEX WITH AN 11-RESIDUE RECRUITMENT PEPTIDE FROM P27

Template:ABSTRACT PUBMED 12501191

Function

[CCNA2_HUMAN] Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

About this Structure

1h27 is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lowe ED, Tews I, Cheng KY, Brown NR, Gul S, Noble ME, Gamblin SJ, Johnson LN. Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A. Biochemistry. 2002 Dec 31;41(52):15625-34. PMID:12501191
  • Brown NR, Noble ME, Endicott JA, Johnson LN. The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Nat Cell Biol. 1999 Nov;1(7):438-43. PMID:10559988 doi:10.1038/15674

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